Effect of RMT on Obstructive Sleep Apnea

Effect of RMT on Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is characterized by a cessation of airflow for more than 10 seconds, leading to arousal and awakening. Hypopnea is a less severe form marked by a greater than 30% reduction of airflow. It is caused by anatomic and/or neuromuscular dysfunction, and is more prevalent with advanced age. OSA and hypopneas lead to transient reductions in blood oxygen levels causing arousal and disruption of normal sleep architecture. The resulting sleep disorders impair:

  • Daytime Activities
  • Cognitive Function
  • Work Performance
  • Quality of Life (QOl)
  • In addition, they can cause hypertension and cardiovascular disease.

    Today’s blog post looks at how OSA can be improved in order to lead to better prognoses for patients as well as an increase in their quality of life. IMT, for example, was tested to see if it can cause an improvement of OSA in patients with mild to moderate forms of the disorder. Let’s take a closer look at the study below.

    Key Findings

    • Obstructive sleep apnea (OSA) is characterized by reduced or stopped airflow, leading to awakening, reductions in blood oxygen levels and disturbed sleep architecture.
    • OSA leads to impaired daytime activities, cognitive function, work performance, quality of life (QOL) and can cause hypertension and cardiovascular disease.
    • 6 weeks of respiratory muscle training (RMT) reduced awakenings, arousals, and limb movements.

    Patient Impact

    RMT effectively improves sleep quantity and quality in people with OSA.

    Study Methods

    A wide variety of variables were addressed throughout the course of this study, including:

    • Sleep (duration, quality, architecture, and apnea hypopnea index)
    • Blood pressure (systolic and diastolic pressures)
    • Plasma catecholamine content (epinephrine, norepinephrine, and dopamine)
    • T lymphocyte populations (pro-inflammatory Th1, Th2, and Th17 helper T cells, cytotoxic T cells, and anti-inflammatory regulatory T cells)

    All of the above were assessed in patients with mild to moderate OSA before and after six weeks of daily IMT. IMT included 30 breaths per day at 75% PImax for six weeks. Results were compared to a low intensity control group.

    Study Results

    IMT resulted in significant reduction of awakening after sleep onset, reduction in arousal per hour or sleep and limb movement, and improvement of sleep quality. Furthermore, IMT lead to increased PImax and significantly lower blood pressure.

    Respiratory muscle training using IMT significantly improves sleep quantity and quality in persons with OSA, reduces apnea and lowers blood pressure.

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    2 Comments

    1. Sandra

      Does having a thornwalt cyst also may also halt breathing at night and/or awakening at night or making to the morning trying to breathe be a factor why this disease persists. I do have sleep equipment.

      Reply
      • PN Medical

        Hi Sandra,

        Thank you so much for reaching out to us regarding your concern. I am more than happy to assist you with this matter!

        RMT has proven beneficial in some studies in patients with CF. Especially in combination with exercise, RMT may increase your respiratory muscle strength, exercise tolerance, and oxygen uptake. In addition, RMT may reduce the frequency of exacerbations. You can ask your physician if the thornwaldt cyst would be an issue for RMT as it is completed with the Breather via mouthpiece. This only requires a small palate to increase a seal by closing off your nasal passage at the nasopharynx. Additionally, it seems like you have a case of sleep apnea, which is likely the culprit of apnea events & awakenings during the nights. In this case I would also recommend you reach out to your health care provider regarding this matter. If you wish to see the benefits of RMT with the Breather and sleep apnea please see this helpful link attached: https://www.pnmedical.com/therapeutic-use/other-diseases/effect-of-rmt-on-sleep-architecture-in-obstructive-sleep-apnea/

        If you have any further questions, please do not hesitate to contact us.

        Kindest regards,

        Quamarul Manna
        PN Medical

        Reply

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