welcome to the long covid recovery study!

If you have tested positive for the SARS-CoV-2 virus 3 or more weeks ago, and/or have been diagnosed with COVID-19, you may be eligible to take part in this research study conducted by the Mayo Clinic in collaboration with PN Medical.

On this page, you will find all the information regarding the COVID Virtual Recovery Study (CVRS). Please read all the information carefully. If you would like to participate in the study, please answer the eligibility questions after reading the patient information.

Update: You are eligible to enroll in the study if you have tested positive at least 3 weeks ago, with no other limitation on how long ago you were treated.



Please read this information carefully.

Information for patients who may be eligible for the clinical trial to test the effectiveness of The Breather/Breather Fit to reduce long-term symptoms of COVID-19.

Why am I being invited to take part in a research study?

You have tested positive for the virus causing COVID-19 (SARS-CoV-2) 3 or more weeks ago and are over 18 years of age.

Why is this research being done?

Investigate the benefits of respiratory muscle training (RMT) using The Breather/Breather Fit and nasal breathing to accelerate recovery from COVID-19: improving COVID-related symptoms, respiratory function, fitness, ability to return to work, cognitive function, and quality of life.

How long will the research last?

We expect that you will be in this research study for 4 weeks.

What happens if I agree to be in this research?

  • You will be asked to download the Breather Coach app onto your smartphone and register.
  • 3 times [at the beginning, week 2, week 4] you will be asked questions regarding your:
    – covid-related medical history
    – underlying diseases you may have
    – your quality of life- your mental health
    – your activity level
  • You will also be asked to perform two tasks:
    – a maximum phonation time test (sound test)
    – a sit-to-stand test.
  • You will receive an RMT device (the Breather or the Breather Fit), and you will be asked to follow a training plan on the Breather Coach app, using the RMT device once or twice per day, am and pm, on a specific number of days per week.
  • You may also be asked to do additional breathing exercises.

The devices will be yours to keep at the end of the study and you will have further access to the Breather Coach app should you wish to continue the training.

Is there any way being in this study could be bad for me?

Use of the Breather/Breather Fit has not been associated with any risks over the past 40 years, we, therefore, believe that no potential health risks are associated with this study. It is possible that you might experience lightheadedness or a brief anxious period due to low air intake when first using the Breather. Should you experience this, you will be advised to stop and rest before continuing. These symptoms should quickly go away, and disappear as you become more comfortable using the Breather.

Will being in this study help me in any way?

Based on the evidence for RMT, we expect that you may benefit from taking part in this study. You might experience an easing of your Covid-related symptoms such as shortness of breath; and you may find it easier to fulfill your daily activities.

We cannot promise any benefits to you or others from taking part in this study. However, possible benefits include improved respiratory muscle strength, reduced difficulty breathing, increased exercise capacity, reduced necessity using bronchodilators or inhalers/nebulizers, reduced blood pressure and heart rate, and improved quality of life. These benefits may continue after the end of the study if you continue RMT.

Signup for this event has been closed.